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Prescribing Antidepressants and Benzodiazepines in the Netherlands: Is Chronic Physical Illness Involved?

机译:在荷兰开处方抗抑郁药和苯二氮卓类药物:是否涉及慢性身体疾病?

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摘要

In this study we assessed differences in new and repeat prescriptions of psycho-tropics between patients receiving prescriptions for drugs to treat a common chronic disease and people without such prescriptions. The study used the databases of two Dutch health insurance companies (3 million people). We selected all Dutch men and women aged 45 and older who were registered for six consecutive years (1999–2004). Our analyses both found a consistent relation between psycho-tropics on the one hand and physical illness on the other. People with multi-morbidity were prescribed these drugs most often, especially men and those younger than 65. Epidemiological studies showed a prevalence of depression among people with multi-morbidity to be twice as high as among people without such conditions. According to recent guidelines non-drug treatment may be the first therapy option for patients with non severe depression. If prescribed for a long time, benzodiazepine prescriptions are especially known to be addictive. Our data raise the question to what extent patients with a chronic physical disease suffering from co-occurring mental problems are prescribed psycho-tropics in accord with the guidelines that also advise mental support in case of non severe mental problems. Further research can answer this important question.
机译:在这项研究中,我们评估了接受新药和新药处方的患者在治疗常见慢性疾病的药物处方药和未使用此类药物的人之间的差异。该研究使用了两家荷兰健康保险公司(300万人)的数据库。我们选择了连续六年(1999-2004年)登记的所有年龄在45岁以上的荷兰男性和女性。我们的分析都发现一方面精神病患者与另一方面身体疾病之间存在一致的关系。患有多种疾病的人最常使用这些药物,尤其是男性和65岁以下的人。流行病学研究显示,患有多种疾病的人的抑郁症患病率是没有这种疾病的人的两倍。根据最新指南,对于非严重抑郁症患者,非药物治疗可能是首选治疗方法。如果长时间开处方,则众所周知苯二氮卓类处方会上瘾。我们的数据提出了这样一个问题,即在某种程度上,患有并发精神疾病的慢性身体疾病患者应根据精神药物处方开具精神药物,该指南还建议在非严重精神疾病的情况下给予精神支持。进一步的研究可以回答这个重要问题。

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